Assessment of new cationic porphyrin binding to plasma proteins by planar microarray and spectroscopic methods
نویسندگان
چکیده
منابع مشابه
DNA groove binding of an asymmetric cationic porphyrin and its Cu(II) complex: Resolved by spectroscopic, viscometric and molecular docking studies
In the present study, the interaction between water-soluble cationic asymmetric porphyrin, 5-(1-Hexadecyl pyridinium-4-yl)-10, 15, 20-tris (1-Butyl pyridinium-4-yl) Porphyrin Chloride, and its copper (II) derivative with calf thymus DNA (CT-DNA) were studied by means of spectroscopic techniques, viscosity measurements and molecular docking. The monitoring of the changes in visible absorbance sp...
متن کاملSyntheses and DNA binding of new cationic porphyrin-tetrapeptide conjugates.
Recently cationic porphyrin-peptide conjugates were synthesized to enhance the cellular uptake of porphyrins or deliver the peptide moiety to the close vicinity of nucleic acids. DNA binding of such compounds was not systematically studied yet. We synthesized two new porphyrin-tetrapeptide conjugates which can be considered as a typical monomer unit corresponding to the branches of porphyrin-po...
متن کاملon the comparison of keyword and semantic-context methods of learning new vocabulary meaning
the rationale behind the present study is that particular learning strategies produce more effective results when applied together. the present study tried to investigate the efficiency of the semantic-context strategy alone with a technique called, keyword method. to clarify the point, the current study seeked to find answer to the following question: are the keyword and semantic-context metho...
15 صفحه اولSynthesis and spectroscopic characterization of two tetrasubstituted cationic porphyrin derivatives.
An imidazolium tetrasubstituted cationic porphyrin derivative (the free base and its Zn(II) complex) with five-membered heterocyclic groups in the meso-positions were synthesized using microwave irradiation, and the compounds obtained characterized by (1)H-NMR and mass spectrometry. We observed that under microwave irradiation the yield is similar to when the synthesis is performed under conven...
متن کاملCharacterizations of cationic γ-carbolines binding with double-stranded DNA by spectroscopic methods and AFM imaging.
Two cationic γ-carbolines, 2-methyl-5H-pyrido[4,3-b]indolium iodide (MPII) and 2,5-dimethyl-5H-pyrido[4,3-b]indolium iodide (DPII), were synthesized, and the DNA-binding properties of the cationic γ-carbolines were elucidated. Through a series of experiments, we proved that the two cationic γ-carbolines could strongly interact with DNA by intercalative binding. However, DPII, with a methyl grou...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biomolecular Structure and Dynamics
سال: 2013
ISSN: 0739-1102,1538-0254
DOI: 10.1080/07391102.2012.703063